KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R2
All Species:
15.45
Human Site:
S58
Identified Species:
37.78
UniProt:
Q13319
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13319
NP_003927.1
367
38705
S58
E
S
R
L
K
R
P
S
V
L
I
S
A
L
T
Chimpanzee
Pan troglodytes
XP_516099
367
38658
S58
E
S
R
L
K
R
P
S
V
L
I
S
A
L
T
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
Q31
V
G
H
Y
T
A
V
Q
N
S
K
N
A
K
D
Dog
Lupus familis
XP_853120
458
47635
S146
E
S
R
L
K
R
P
S
V
L
I
S
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
S58
E
S
R
L
K
R
P
S
V
L
I
S
A
L
T
Rat
Rattus norvegicus
P61810
307
34013
Q31
V
G
H
Y
T
A
V
Q
N
S
K
N
A
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089375
320
35634
S44
S
K
N
G
G
S
K
S
E
K
T
L
K
R
H
Zebra Danio
Brachydanio rerio
NP_001017569
308
34577
S31
A
S
G
K
T
E
K
S
L
K
R
H
S
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
N49
T
S
S
R
S
S
S
N
A
K
E
S
V
L
M
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
N60
E
R
P
M
R
K
H
N
S
A
L
F
I
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
49.5
77.2
N.A.
94.3
48.7
N.A.
N.A.
N.A.
58.3
55.5
N.A.
N.A.
N.A.
31.6
36.5
Protein Similarity:
100
99.7
59.1
77.7
N.A.
94.8
58.5
N.A.
N.A.
N.A.
64.5
64.8
N.A.
N.A.
N.A.
42.5
49.8
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
N.A.
N.A.
6.6
33.3
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
20
0
0
10
10
0
0
60
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% D
% Glu:
50
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
20
10
10
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
20
0
0
0
10
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
40
0
10
0
0
% I
% Lys:
0
10
0
10
40
10
20
0
0
30
20
0
10
20
0
% K
% Leu:
0
0
0
40
0
0
0
0
10
40
10
10
0
50
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
20
20
0
0
20
0
0
0
% N
% Pro:
0
0
10
0
0
0
40
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% Q
% Arg:
0
10
40
10
10
40
0
0
0
0
10
0
0
10
0
% R
% Ser:
10
60
10
0
10
20
10
60
10
20
0
50
10
10
0
% S
% Thr:
10
0
0
0
30
0
0
0
0
0
10
0
0
0
40
% T
% Val:
20
0
0
0
0
0
20
0
40
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _